Site performance diagnostics
Trace a stalled study from feasibility through enrollment and identify the operational constraints behind the numbers.
Explore site performance diagnostics →Atlanta, Georgia · Clinical trial site performance
Trials move at the speed of site execution.
Cadence works with oncology and complex research teams to strengthen the work between protocol and patient: feasibility, study start-up, enrollment, quality, workflow, and day-to-day site operations.
Atlanta-based senior site-side support. Available for remote and on-site engagements across Georgia and the Southeast. Learn about our regional reach.
15 yearsin research, including nine years in oncology and genitourinary clinical trials
20+Phase I-IV NIH-funded and industry-sponsored studies managed in a current portfolio
40%shorter activation timelines achieved in prior site leadership work
45+clinical research professionals mentored
The operating gap
A sound protocol can still underperform at the site.
Activation drifts. A handoff between clinic and research goes quiet. Monitoring actions remain open. Coordinators work around a process instead of through it. Eligible participants never reach consent.
We start with the team and the evidence already available: how the work actually moves, where it waits, what the data shows, and which change is most likely to improve execution without adding unnecessary complexity.
Where we help
Practical support for the parts of a trial a site can actually control.
Engagements are scoped around a defined operational problem rather than a broad transformation program. Start with one study, one workflow, or one portfolio constraint.
Start-up & activation readiness
Strengthen feasibility, start-up ownership, regulatory handoffs, budget and contract coordination, and activation workflow.
See start-up and activation support →Enrollment & participant pathway
Map identification, prescreening, eligibility, approach, consent, and follow-through so loss points become visible and actionable.
Review enrollment pathway consulting →Quality & inspection readiness
Review monitoring follow-up, CAPA closure, eTMF organization, delegation controls, and site documentation habits before they become findings.
Explore quality and inspection readiness →Clinical trial enrollment is a process
Stop reporting one number. Start managing the transitions.
Low patient enrollment is a symptom. The useful question is where participants are being lost: identification, prescreening, eligibility, approach, consent, or scheduling.
Cadence helps teams instrument the pathway, isolate the constraint, and focus effort where it can change performance. See our guide to why GU clinical trials stall at screening.
Participant pathwayIllustrative workflow
Identified01
Prescreened02
Approached03
Enrolled04
The shape is conceptual, not a performance benchmark. Actual analysis uses the site's own study data.
Who we serve
Built for teams close enough to the work to change it.
Cadence is intentionally site-centered. We work best where leaders want experienced operational perspective, candid collaboration, and changes the research team can sustain.
Research institutions & site networks
Portfolio, activation, enrollment, and site-quality problems across oncology and complex research programs.
Research sites
Workflow redesign, team operating rhythm, inspection readiness, and study execution.
Principal investigators
A structured operational review when a study is open but not moving as expected.
Sponsors & CRO partners
Site-side perspective on feasibility, activation, monitoring follow-up, and operational friction.
Experience behind the work
Site leadership across the full study lifecycle.
Cadence's clinical strategy is led by Sierra Williams Thomson, a research leader with fifteen years in research, including nine years concentrated in oncology and genitourinary clinical trials.
2
investigator-initiated Phase 2 clear cell renal cell carcinoma trials carried from start-up to full enrollment
15+
staff managed across the employee lifecycle in site leadership roles
Peer reviewed
named author on oncology/GU publications and abstracts, including work presented at ASCO GU
Clinical trial site operations insights
Field notes for research teams running the work.
Practical guidance on enrollment, feasibility, study start-up, monitoring follow-up, CAPA, quality, and the workflow between a protocol and an enrolled participant.
Atlanta, Georgia · Start with one constraint
Bring us the study or site process that is not moving.
We will start with the evidence, listen to the people closest to the work, define the operating problem, and tell you candidly whether Cadence is the right fit to help.